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2024

L. Fan, Choy, J. S., Cai, C., Teague, S. D., Guccione, J., Lee, L. Chuan, and Kassab, G. S., “Comparison of Left Ventricular Function Derived from Subject-Specific Inverse Finite Element Modeling Based on 3D ECHO and Magnetic Resonance Images”, Bioengineering, vol. 11, 2024.

J. Derick Abraham, Shavik, S. Mohammad, Mitchell, T. R., Lee, L. Chuan, Ray, B., and Leonardi, C. R., “Computational investigation of the role of ventricular remodelling in HFpEF: The key to phenotype dissection”, Computers in Biology and Medicine, vol. 180, p. 109019, 2024.

J. Derick Abraham, Shavik, S. Mohammad, Mitchell, T. R., Lee, L. Chuan, Ray, B., and Leonardi, C. R., “Computational investigation of the role of ventricular remodelling in HFpEF: The key to phenotype dissection”, Computers in Biology and Medicine, vol. 180, p. 109019, 2024.

H. Wang, Fan, L., Choy, J. S., Kassab, G. S., and Lee, L. Chuan, “Mechanisms of coronary sinus reducer for treatment of myocardial ischemia: in silico study”, Journal of Applied Physiology, vol. 136, pp. 1157–1169, 2024.

H. Sharifi, Lee, L. Chuan, Campbell, K. S., and Wenk, J. F., “A multiscale finite element model of left ventricular mechanics incorporating baroreflex regulation”, Computers in Biology and Medicine, vol. 168, p. 107690, 2024.

H. Sharifi, Mehri, M., Mann, C. K., Campbell, K. S., Lee, L. Chuan, and Wenk, J. F., “Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease”, Annals of Biomedical Engineering, pp. 1–15, 2024.

J. S. Choy, Hubbard, T., Wang, H., Awakeem, Y., Khosravi, P., Khadivi, B., Navia, J. A., Stone, G. W., Lee, L. Chuan, and Kassab, G. S., “Preconditioning with selective autoretroperfusion: In vivo and in silico evidence of washout hypothesis”, Frontiers in Bioengineering and Biotechnology, vol. 12, p. 1386713, 2024.

E. Naghavi, Wang, H., Fan, L., Choy, J. S., Kassab, G., Baek, S., and Lee, L. - C., “Rapid estimation of left ventricular contractility with a physics-informed neural network inverse modeling approach”, Artificial Intelligence in Medicine, vol. 157, p. 102995, 2024.

L. Fan, Wang, H., Kassab, G. S., and Lee, L. Chuan, “Review of cardiac–coronary interaction and insights from mathematical modeling”, WIREs Mechanisms of Disease, vol. 16, p. e1642, 2024.

H. Wang, Fan, L., Choy, J. S., Kassab, G. S., and Lee, L. Chuan, “Simulation of coronary capillary transit time based on full vascular model of the heart”, Computer Methods and Programs in Biomedicine, vol. 243, p. 107908, 2024.

2023

J. Mojumder, Fan, L., Nguyen, T., Campbell, K. S., Wenk, J. F., Guccione, J. M., Abraham, T., and Lee, L. Chuan, “Computational analysis of ventricular mechanics in hypertrophic cardiomyopathy patients”, Scientific Reports, vol. 13, p. 958, 2023.

T. Patel, Li, C., Raissi, F., Kassab, G. S., Gao, T., and Lee, L. Chuan, “Coupled thermal-hemodynamics computational modeling of cryoballoon ablation for pulmonary vein isolation”, Computers in Biology and Medicine, vol. 157, p. 106766, 2023.

T. Patel, Li, C., Raissi, F., Kassab, G. S., Gao, T., and Lee, L. Chuan, “Coupled thermal-hemodynamics computational modeling of cryoballoon ablation for pulmonary vein isolation”, Computers in Biology and Medicine, vol. 157, p. 106766, 2023.

L. Green, Chan, W. Xuan, Ren, M., Mattar, C. Nurfarah Z., Lee, L. Chuan, and Yap, C. Hwai, “The dependency of fetal left ventricular biomechanics function on myocardium helix angle configuration”, Biomechanics and Modeling in Mechanobiology, vol. 22, pp. 629–643, 2023.

J. Sundnes, Lee, L. Chuan, Wall, S. T., and Valdez-Jasso, D., “Editorial: Computational models of cardiovascular growth and remodeling”, Frontiers in Physiology, vol. 14, 2023.

L. Fan, Choy, J. S., Lee, S., Campbell, K. S., Wenk, J. F., Kassab, G. S., Burkhoff, D., and Lee, L. Chuan, “An in silico study of the effects of left ventricular assist device on right ventricular function and inter-ventricular interaction”, Artificial Organs, vol. 47, pp. 1831–1847, 2023.

L. Fan, Choy, J. S., Lee, S., Campbell, K. S., Wenk, J. F., Kassab, G. S., Burkhoff, D., and Lee, L. Chuan, “An in silico study of the effects of left ventricular assist device on right ventricular function and inter-ventricular interaction”, Artificial Organs, vol. 47, pp. 1831–1847, 2023.

2022

R. Pourmodheji, Jiang, Z., Tossas-Betancourt, C., Dorfman, A. L., C Figueroa, A., Baek, S., and Lee, L. - C., “Computational modelling of multi-temporal ventricular–vascular interactions during the progression of pulmonary arterial hypertension”, Journal of the Royal Society Interface, vol. 19, p. 20220534, 2022.

C. Tossas-Betancourt, Li, N. Y., Shavik, S. M., Afton, K., Beckman, B., Whiteside, W., Olive, M. K., Lim, H. M., Lu, J. C., Phelps, C. M., and , “Data-driven computational models of ventricular-arterial hemodynamics in pediatric pulmonary arterial hypertension”, Frontiers in Physiology, p. 1744, 2022.

C. Tossas-Betancourt, Li, N. Y., Shavik, S. M., Afton, K., Beckman, B., Whiteside, W., Olive, M. K., Lim, H. M., Lu, J. C., Phelps, C. M., and , “Data-driven computational models of ventricular-arterial hemodynamics in pediatric pulmonary arterial hypertension”, Frontiers in Physiology, p. 1744, 2022.

C. Tossas-Betancourt, Li, N. Y., Shavik, S. M., Afton, K., Beckman, B., Whiteside, W., Olive, M. K., Lim, H. M., Lu, J. C., Phelps, C. M., and , “Data-driven computational models of ventricular-arterial hemodynamics in pediatric pulmonary arterial hypertension”, Frontiers in Physiology, p. 1744, 2022.

L. Green, Chan, W. Xuan, Ren, M., Mattar, C. Nurfarah Z., Lee, L. Chuan, and Yap, C. Hwai, “The dependency of fetal left ventricular biomechanics function on myocardium helix angle configuration”, Biomechanics and Modeling in Mechanobiology, pp. 1–15, 2022.

L. Fan, Sun, Y., Choy, J. S., Kassab, G. S., and Lee, L. Chuan, “Mechanism of exercise intolerance in heart diseases predicted by a computer model of myocardial demand-supply feedback system”, Computer Methods and Programs in Biomedicine, vol. 227, p. 107188, 2022.

Y. Zheng, Chan, W. Xuan, Charles, C. J., Richards, A. Mark, Lee, L. Chuan, Leo, H. Liang, and Yap, C. Hwai, “Morphological, functional, and biomechanical progression of LV remodelling in a porcine model of HFpEF”, Journal of Biomechanics, vol. 144, p. 111348, 2022.

Y. Zheng, Chan, W. Xuan, Charles, C. J., Richards, A. Mark, Lee, L. Chuan, Leo, H. Liang, and Yap, C. Hwai, “Morphological, functional, and biomechanical progression of LV remodelling in a porcine model of HFpEF”, Journal of Biomechanics, vol. 144, p. 111348, 2022.

L. Fan, Choy, J. S., Raissi, F., Kassab, G. S., and Lee, L. Chuan, “Optimization of cardiac resynchronization therapy based on a cardiac electromechanics-perfusion computational model”, Computers in Biology and Medicine, vol. 141, 2022.

2021

C. Wei Ong, Ren, M., Wiputra, H., Mojumder, J., Chan, W. Xuan, Tulzer, A., Tulzer, G., Buist, M. Lindsay, Mattar, C. Nurfarah Z., Lee, L. Chuan, and Yap, C. Hwai, “Biomechanics of Human Fetal Hearts with Critical Aortic Stenosis”, Annals of biomedical engineering, vol. 49, no. 5, 2021.

C. Hwai Yap, Ong, C. Wei, Ren, M., Wiputra, H., Mojumder, J., Tulzer, A., Tulzer, G., Buist, M., Mattar, C. Nurfarah Z., and Lee, L. Chuan, “BS14 Image-based computatinoal simulations of foetal heart function to understand congenital malformations and foetal heart intervention”, vol. 107, no. Suppl 1, 2021.

S. Mohammad Shavik, Wall, S., Sundnes, J., Guccione, J. M., Sengupta, P., Solomon, S. D., Burkhoff, D., and Lee, L. Chuan, “Computational Modeling Studies of the Roles of Left Ventricular Geometry, Afterload, and Muscle Contractility on Myocardial Strains in Heart Failure with Preserved Ejection Fraction”, Journal of cardiovascular translational research, vol. 14, no. 6, 2021.

C. Hwai, Ong, C. Wei, Ren, M., Wiputra, H., Mojumder, J., Tulzer, A., Tulzer, G., Buist, M., Mattar, C. Nurfarah Z., and Lee, L. Chuan, “IMAGE-BASED COMPUTATINOAL SIMULATIONS OF FOETAL HEART FUNCTION TO UNDERSTAND CONGENITAL MALFORMATIONS AND FOETAL HEART INTERVENTION”, in HEART, 2021.

R. Pourmodheji, Jiang, Z., Tossas-Betancourt, C., C Figueroa, A., Baek, S., and Lee, L. - C., “Inverse modeling framework for characterizing patient-specific microstructural changes in the pulmonary arteries”, Journal of the Mechanical Behavior of Biomedical Materials, vol. 119, 2021.

M. R. Grobbel, Lee, L. C., Watts, S. W., Fink, G. D., and Roccabianca, S., “Left Ventricular Geometry, Tissue Composition, and Residual Stress in High Fat Diet Dahl-Salt Sensitive Rats”, Experimental Mechanics, 2021.

J. Mojumder, Choy, J. S., L Leng, Z. S., Kassab, G. S., and Lee, L. C., “Mechanical stimuli for left ventricular growth during pressure overload”, Experimental mechanics, 2021.

J. Mojumder, Choy, J. S., L Leng, Z. S., Kassab, G. S., and Lee, L. C., “Mechanical stimuli for left ventricular growth during pressure overload”, Experimental mechanics, 2021.

H. Sharifi, Mann, C. K., Rockward, A. L., Mehri, M., Mojumder, J., Lee, L. - C., Campbell, K. S., and Wenk, J. F., “Multiscale simulations of left ventricular growth and remodeling”, vol. 13, no. 5, 2021.

B. A. Zambrano, McLean, N., Zhao, X., Le Tan, J. -, Zhong, L., C Figueroa, A., Lee, L. Chuan, and Baek, S., “Patient-specific computational analysis of hemodynamics and wall mechanics and their interactions in pulmonary arterial hypertension”, Frontiers in bioengineering and biotechnology, vol. 8, p. 611149, 2021.

B. A. Zambrano, McLean, N., Zhao, X., Le Tan, J. -, Zhong, L., C Figueroa, A., Lee, L. Chuan, and Baek, S., “Patient-specific computational analysis of hemodynamics and wall mechanics and their interactions in pulmonary arterial hypertension”, Frontiers in bioengineering and biotechnology, vol. 8, p. 611149, 2021.

L. Fan, Namani, R., Choy, J. S., Awakeem, Y., Kassab, G. S., and Lee, L. Chuan, “Role of coronary flow regulation and cardiac-coronary coupling in mechanical dyssynchrony associated with right ventricular pacing”, American Journal of Physiology-Heart and Circulatory Physiology, 2021.

L. Fan, Namani, R., Choy, J. S., Kassab, G. S., and Lee, L. Chuan, “Transmural distribution of coronary perfusion and myocardial work density due to alterations in ventricular loading, geometry and contractility”, Frontiers in Physiology, p. 2105, 2021.

2020

L. Fan, Namani, R., Choy, J. S., Kassab, G. S., and Lee, L. Chuan, “Effects of mechanical dyssynchrony on coronary flow: insights from a computational model of coupled coronary perfusion with systemic circulation”, Frontiers in physiology, 2020.

R. Namani, Lee, L. C., Lanir, Y., Kaimovitz, B., Shavik, S. M., and Kassab, G. S., “Effects of myocardial function and systemic circulation on regional coronary perfusion”, Journal of Applied Physiology, 2020.

R. Namani, Lee, L. C., Lanir, Y., Kaimovitz, B., Shavik, S. M., and Kassab, G. S., “Effects of myocardial function and systemic circulation on regional coronary perfusion”, Journal of Applied Physiology, 2020.

C. K. Mann, Lee, L. Chuan, Campbell, K. S., and Wenk, J. F., “Force-dependent recruitment from myosin OFF-state increases end-systolic pressure–volume relationship in left ventricle”, Biomechanics and modeling in mechanobiology, 2020.

S. Mohammad Shavik, Tossas-Betancourt, C., C Figueroa, A., Baek, S., and Lee, L. Chuan, “Multiscale modeling framework of ventricular-arterial bi-directional interactions in the cardiopulmonary circulation”, Frontiers in physiology, 2020.

R. Namani, Lanir, Y., Lee, L. Chuan, and Kassab, G. S., “Overview of mathematical modeling of myocardial blood flow regulation”, American Journal of Physiology-Heart and Circulatory Physiology, 2020.

R. Namani, Lanir, Y., Lee, L. Chuan, and Kassab, G. S., “Overview of mathematical modeling of myocardial blood flow regulation”, American Journal of Physiology-Heart and Circulatory Physiology, 2020.

H. Zou, Leng, S., Xi, C., Zhao, X., Koh, A. S., Gao, F., Le Tan, J., San Tan, R. -, Allen, J. C., Lee, L. Chuan, Genet, M., and Zhong, L., “Three-dimensional biventricular strains in pulmonary arterial hypertension patients using hyperelastic warping”, Computer methods and programs in biomedicine, 2020.

H. Zou, Leng, S., Xi, C., Zhao, X., Koh, A. S., Gao, F., Le Tan, J., San Tan, R. -, Allen, J. C., Lee, L. Chuan, Genet, M., and Zhong, L., “Three-dimensional biventricular strains in pulmonary arterial hypertension patients using hyperelastic warping”, Computer methods and programs in biomedicine, 2020.

H. Zou, Leng, S., Xi, C., Zhao, X., Koh, A. S., Gao, F., Le Tan, J., San Tan, R. -, Allen, J. C., Lee, L. Chuan, Genet, M., and Zhong, L., “Three-dimensional biventricular strains in pulmonary arterial hypertension patients using hyperelastic warping”, Computer methods and programs in biomedicine, 2020.

2019

K. S. Campbell, Yengo, C. M., Lee, L. - C., Kotter, J., Sorrell, V. L., Guglin, M., and Wenk, J. F., “Closing the therapeutic loop”, 2019.

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